The choice of the Microsoft ASP.NET version depends on the code generated for the website.
Opt for version 3.5 for ASP.NET versions 2.0–3.5 and version 4.5 for ASP.NET versions 4.0 and above.
There are two methods to set the ASP.NET version in Plesk:
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Through Hosting Settings
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Through ASP.NET Settings.
Here are the instructions for configuring the ASP.NET version in Plesk using Hosting Settings:
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Log in to the Plesk control panel using your login credentials.
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Choose the "Websites & Domains" option from the dashboard's left corner.
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Next, select the "Hosting Settings" icon.
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Within the Web scripting and statistics section, pick the desired version of Microsoft ASP.NET support from the drop-down box. Click the OK button once you have selected the necessary version.
Here are the steps to configure the ASP.NET version in Plesk from the ASP.NET Settings:
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Log in to the Plesk control panel by entering your login credentials.
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Choose the "Websites & Domains" option from the left corner of the dashboard.
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Click on the "ASP.NET Settings" icon.
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Choose "Change Version."
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In the "Selecting the ASP.NET Version" window, pick the required version and click OK.
That's it!
This is how you can successfully configure the ASP.NET version for a website in Plesk.